ABSTRACT
Hair growth and developments are influenced by androgens. Androgens are important in hair growth and patterning in men. Reports on hormone analysis in androgenetic hair loss in females show partly contradicting results elevated as well as normal-range androgens levels have been found. To determine the nature of the hormonal status in patients with AGA and to evaluate the saliva as new clinical tool in hormonal parameters, this study was carried out on 30 subjects with AGA and 20 subjects without AGA as controls. FT and DREA-S in the serum and saliva were measured in all subjects There was significant increase in both hormone levels in the serum of bald men while no significant changes were noted in the serum of bald women. Also saliva FT showed significant increase in bald men and women; while saliva DHEA-S showed significant increase only in the bald women in comparison to control. [1] Men with higher levels of androgens are more likely to have AGA. [2]-increased response of androgen receptors in the skin despite normal androgens levels seems to play a causal role in female patients with AGA [3] The saliva/plasma relationship is not yet sufficiently understood to assess the value of salivary measurements in patients with AGA-Further investigations are recommended to find answers to these problems